Yes, you can connect two Quick Keys to your Pen Display 16 and give them unique names to help you distinguish between the two.
You will need to pair one of the Quick Keys with the wireless dongle on the Pen Display 16. I have placed a link below to an FAQ that will walk you through the process.
FAQ Pairing Link: https://solutions.xencelabs.com/en/support/solutions/articles/67000400865-can-i-pair-my-tablet-or-quick-keys-to-a-different-xencelabs-wireless-dongle-