Xencelabs Technologies Ltd.

Yes, you can color-calibrate your Pen Display 24. Before you do so, you should warm it up for 30 minutes or more and set the color space in the Settings panel to Pantone. 

The instructions below will walk you through setting the Pen Display 24 to the Pantone color space.

I have tested with the Datacolor Spyder Pro and the X-Rite i1 Profiler, and they both work well.

With the Settings panel open, [1] If you have more than one Xencelabs device connected to your computer, select your Pen Display 24 from the top device selection row. [2] Then, Select Device Settings. [3] Select Color Settings. [4] Then select Pantone.